Tuesday, August 4, 2015

Cannabis, Carrier Oils and Apoptosis of Cancer Cells

What is Apoptosis?

According to National Center for Biotechnology Information (NCBI) a multicellular organism’s (Human) cells are members of a highly structured community. The quantity of cells in the community is regulated efficiently by governing the rate of cell mitosis as well as controlling the rate of cell death. When a cell is no longer needed, an intracellular death program is initiated that causes a cell to essentially commit suicide. This process is known as programmed cell death, medically and scientifically known as apoptosis which is drawn from a Greek word meaning “falling off.”

Why is Apoptosis so important to a cancer patient?

Some oncogenic mutations or precancerous lesions actually disrupt the mechanism of apoptosis, leading to tumor origination, progression or metastasis. This means that when the cells continue to divide and multiply, but do not die, cancer begins, grows and spreads. This is when cancer treatments are necessary.

Treatment Options

Cancer patients are offered a variety of treatment options that usually include Chemotherapy, Radiotherapy and steroid therapy in different combinations and doses all with the same goal in mind: causing “Apoptosis” of malignant cells. These therapies though, are very toxic and overwhelming to the human body, leaving the patient very sick and frail, fighting for their lives. Radiation and chemotherapy force apoptosis in cancer cells, but these drugs cannot tell the difference between healthy cells and malignant cells – they kill all cells indiscriminately, this is the downfall to a pharmaceutical approach.

In the past decade the demand for less toxic more natural approaches to treating diseases including cancer has risen. Information about natural supplements, treatment concoctions and antioxidant-rich diets has flooded the internet. This allows patients and loved ones do their own research, and find what alternative therapy options may work for them. There is also a downfall to this approach; there is a plethora of inaccurate information that may lead people astray on their quest for health. It takes a great deal of research and critical thinking to come to an accurate conclusion.

Plant induced Apoptosis

Medical Cannabis patients have been professing the benefits cannabis has on their health for decades. The government has done research that has revealed some stunning facts about the plant that have been revealed as well as patented. The active compounds found in the plant, THC and CBD were found to be both antiproliferative and pro-apoptotic amongst other things. This means that the compounds actually arrest the spread of cancer as well as causing “apoptosis” of cancer cells.
The remarkable feature that apoptosis via cannabis possesses, is its ability to decipher between healthy and malignant cells, activating apoptosis selectively. By activating the endocannabinoid system, you actually enhance the efficacy of the human immune system by moderating it; this is why cannabis is also therapeutic to autoimmune diseases. The active metabolites attach to your receptors and allow the body to function in a state of balanced homeostasis.

Standard Cannabis Therapy

The most well-known and popular method of cannabis consumption is smoking the flower or buds. When treating a disease, this is actually the least effective method of use. The most therapeutic method of use is ingestion of concentrated cannabis essential oils. There are broad range of names for these concentrates, but do not feel overwhelmed. The easiest way to find what you are looking for is to ask for ethanol extracted cannabis oil. This will product will carry different names such as Rick Simpson Oil (RSO) Full-Extract Cannabis Oil (FECO) and others like it.

Extraction of plant essential oils with alcohol is an age old technique and it is still applied today. There are other beneficial forms of cannabis extracts such as steam distillation, Rosin Technique, Co2 extraction and more. However, in my experience the ethanol extract is one of the most widely available, versatile and therapeutically effective medicinal products derived from cannabis.

The raw whole plant extract is made with either just the buds or buds, trim, seed and stem. The difference is in purity level, each has its own benefits and downfalls. The oil most regularly is found stored in 1-10 gram oral syringes or pre dosed in capsules. Cannabis oil is dark amber or greenish oil that looks black in concentrated amounts. You can use this for almost every medical application you will attempt with cannabis from smoking to ingestion and topical application.

Enhancing Cannabis Therapy

While treating Cancer, efficacy of treatment is a huge factor in achieving remission. Increasing the bioavailability of the oil, or better yet, the compounds within the oil is the goal when you set out to enhance the effectiveness of your medicine. Ingesting raw cannabis oil is very effective, but a large portion of what you eat is wasted. The bio-availability of raw cannabis oil is about 25-40%; this means your body will absorb that much of your dose. There are ways to increase the bioavailability of your oil by infusing it into other essential oils or combining it with other plant materials that are also pro-apoptotic or antioxidant in nature.

Carrier Oils

Carrier oils are called this because they “carry” essential oils into the skin or tissues and bloodstream depending on internal or topical use. Carrier oils aid in the absorption of cannabinoids by making them more bioavailable. Cannabinoids from Cannabis are the primary components of cannabis essential oil; these compounds will be suspended within the carrier oil and brought into the system at a much higher rate than before. It is estimated that Carrier oils increase the absorption of cannabis oil from 25-40% to 75-80%. That is nearly doubling the rate of absorption. This saves money by allowing a smaller more effective dose to be consumed with the same rate of efficacy. 

Each Carrier oil comes with their own individual nutritional benefits. Coconut oil is high in Medium Chain Triglycerides (MCTs) which are an optimum fuel source for the body’s mitochondria. Apricot Kernel oil is high in Linoleic and Oleic acids with are Essential fatty acids (EFAs), but more importantly Apricot kernel oil has a very hard to come by component: Amygdalin or vitamin B 17. Amygdalin is very highly regarded and potent anti-cancer agent that nature provides, it is found in the soft kernels within the apricot pit. When amygdalin is extracted, purified and concentrated it becomes what is known as Laetrile. Amygdalin or Laetrile causes Apoptosis as well. Pumpkin Seed oil is one of the most highly nutritious seed oils there are with a complex and balanced broad spectrum of EFAs vitamins and minerals. Each of the following oils would make excellent carrier oils as well as conjunctive therapeutic agents for Cannabis oil.

A. Coconut Oil
B. Apricot Kernel oil
C. Grapeseed Oil
D. Olive Oil
E. Pomegranate Seed oil
F. Pumpkin Seed oil

Infusing Cannabis oil into these carrier oils is one of the most efficient treatment routes one can take in the natural medicine realm. I always recommend beginning with Coconut oil or Olive oil as these can stand higher heat and take the least amount of preparation and exertion to infuse, and use daily. Do not be afraid to experiment and find what works best for you and your personal lifestyle and diagnosis. Every person is unique just as is every single disease process. Cannabis oil is not the answer alone, fully recovering from any disease requires lifestyle and dietary modifications. You must work to bring your being back into homeostasis and balance your physical, mental and emotional energy centers. Cannabis oil is a very empowering and effective start to regaining your life and health.
Recommended Links:

Dosing Instructions: Cannabis Oil Dosing For Children And Beginners
Carrier Oils: Rose Mountain Herbs


Friday, July 3, 2015

The Portland Oregon #BurnsideBurn

The Burnside Burn, an infamous night on Burnside Bridge in Portland Oregon. This night was the eve of the end of Cannabis prohibition in Oregon. This night there was to be a free weed and seed giveaway, this night there was to be a smoke out on Burnside bridge, this night was to make history.

With the passage of Oregon's Measure 91 last November by voters, recreational marijuana growth, possession, sales and consumption were legalized in the state. On July 1st, 2015 the law went into effect at midnight. Across the state veteran smokers and curious first-timers alike sparked up bowls and joints of high-quality Oregon grown cannabis to herald the new freedom. Portland though, Portland Oregon naturally kept it weird and created beautiful chaos that captured the attention of the entire nation.

The Uber Positive Pork Chop of Portland~

A man named Pork Chop, a very dedicated, obstreperous and irresponsibly loud activist decided that he would take it upon himself to shut down the Burnside bridge. In the months preceding Oregon's official implementation of measure 91 he rallied people around his idea, even calling me during the Rose festival, until he caught the attention of larger area activists like Russ Belville president of Oregon's chapter of NORML (National Organization for the Reform of Marijuana Laws) who aided in publicizing and organizing the event.

Pork Chop became a celebrity overnight for gathering a line of thousands behind him, like the pied piper, with the promise to give away 420 pounds of cannabis flower to bystanders 21 and over. He captured the hearts and minds with the  of the crowd with the promise of the large amount of free weed and with chants like "Fuck the DEA" and "Free The Weed", he gave out a handful of joints and free seeds to people, myself included.

Making Weed NORML

Russ Belville, founder of www.420radio.org and president of NORML Portland, brought plenty of attention to the event on his various platforms, inviting people to join in the fun atop the Burnside bridge at 11:30 on the eve of legalization in Oregon in anticipation of a public smoke-out that was to take place at midnight. He brought the maximum allowable according to the new state law, and smoked with friends and those close by at midnight along with 90% of those on the bridge. The group from NORML were able to gather the bulk of the revelers near the iconic Portland Stag sign, making photo history happen.

The #BurnsideBurn

When the crowd announced that it was midnight there was a collective cheer and thousands of BIC lighters clicking in unison as people excitedly celebrated their newly legal status, within minutes a giant cloud of smoke began emanating from the Burnside bridge. Sporadic coughing and loud shouts brought full realization to the nely relaxed marijuana laws in the state of Oregon. This giant smoke session signaled the death of Cannabis prohibition in Oregon, one of five US states to do so.

The Crowd

There were easily over 2500 people gathered on the infamous Burnside bridge in Portland spanning over the Willamette River. Some eagerly awaited free cannabis, others were content with just being a part of the highly energetic and populated albeit random event that took place in standard peaceful protest fashion, permitless. This gathering of spirits revealed the diverse peoples and cultures who were brought together in this one moment to celebrate a common ground. I heard a number of foreign languages spoken in excited tones no doubt talking about the change in law. People traveled from across the country, even as far as Tennessee and New York; some were from as far away as Canada.

The City-

The city of Portland, Oregon got very stoned this night as giant clouds of marijuana smoke rolled past their bedroom windows that were left open to enjoy a nice willamette valley summer breeze. They awoke the next morning feeling rejuventated and revitalized and had a lot of interesting local news to read about.

Check out the hashtag #Burnsideburn on Instagram and Facebook.


More Reading:
Dope Magazine

Portland Oregon Legal Weed Hash Marijuana Photos Burnside Burn Cannabis Pot Reefer Legalized Pacific Northwest Recreational Medical Dispensary Pork Chop Brandon Krenzler Russ Belville 420 Radio PDX Willamette Multnomah Measure 91 stoned blaze smokeout smoke clouds green buds free seeds stumptown bridgecity ommp police stoners potheads prohibition sativa indica Burnside Bridge history travel peace love

Thursday, July 2, 2015

Free Weed Seeds in Oregon

Jenifer Valley & Mike Mullins founders of Stoney Girl Gardens

With traffic at a stand-still, backed up for 6 miles on highways 212 and 205, the Stoney Girl Gardens commemorative free marijuana seed giveaway was a giant success and a full realization of the newly legalized cannabis laws in Oregon. Ten thousand seeds of cannabis, derived from six signature Stoney Girl strains were given away to anyone twenty-one or older today.

Military veterans, school teachers, ice cream men, UPS drivers and more filed through the alleyway directly behind their soon to open Clackamas cannabis dispensary, Stoney Only. The Stoney Girl team comprised of their gardeners, office personnel and more were present to check ID, cook free food, and hand out seeds to eager visitors. Over 8,000 visitors appeared at the HWY 212 location, next to “Ole’s Medium Rare” steakhouse bar. The dispensary which is under renovation was open for tours to give the public a personalized cannabis experience that doesn’t have to be lived vicariously through media headlines.   

When asked about the company marijuana seed giveaway, Jenifer Valley aka Stoney Girl said, “It felt really amazing to be a part of history, I know this is going to cause a lot of change here in Oregon, and it will give 10,000 people the opportunity to grow their own cannabis.”

News crews were present to interview and film the giveaway, which directed people where to go. Documentary filmmakers Mike and Amy McDermott of “Studio Mcdermott” were in attendance to gather content at this historical happening for their film developing film, “Oregon: The State of Cannabis.” Amy McDermott said, “ What impressed me most at today’s free seed giveaway was the older folks picking up seeds. There will be a lot of grandmothers in Oregon growing cannabis this summer.

Erin Purchase, pediatric cannabis therapy patient, Brave Mykayla’s mother, who also works closely with the seed company, was present jubilantly handing out seeds, reminding people about the therapeutic benefits of medical marijuana and what it did for her daughter during her successful fight with childhood leukemia. She had this to say about the giveaway, “Today to me was a celebration for all the hard work that every activist has put into ending prohibition. I felt honored to take part the largest seed giveaway that has ever taken place on American soil. When the truckers honked in frustration at the waiting line of cars, it made me happy that so many people wanted to come get free seeds to grow legally, and it made our collective effort seem like a real accomplishment” 

This is the first time an American Cannabis seed company has openly and publicly handed out the still federally illegal seeds, let alone 10,000 of them. A local marijuana edible company, Mr. Ucked Up, had a booth from which they were gifting of age passersby with hash infused otter pops and frozen concentrate infused chocolates. Neighbor Dave’s Organics teamed up with Stoney Girl gardens at the giveaway and handed out free gram bags of high-grade organic cannabis flower.

The number of seeds given away today as gifts to the citizens of Oregon was stunning. 10,000 marijuana seeds, which will be planted and grown by Oregonians. The end of Cannabis prohibition came to Oregon today, July 1st, 2015. It was replaced with revelry and generosity. The team at Stoney Girl Gardens has done Oregon a service, it has given people the opportunity to grow their own marijuana, and share it with others; paying forward what was done for them today by Jenifer Valley and Michael Mullins, the founders of Stoney Girl gardens.

This is what a free marijuana seed giveaway looks like~


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